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GLP certified testing of xenobiotics and chemicals

Proposal Number : 1104804       Provide business supports
Date Date of Registration : Aug 12, 2008
Date of Revision : Feb 17, 2015
Country / AreaMecklenburg-Vorpommern, Germany 
Proposal Category 5203 Research and information agency businesses
8802 Bio-medicine and therapeutics (vaccines, biological products, bio-diagnostics / pharmaceuticals, gene-diagnostics / therapeutics )
0403 Pharmaceutical materials, pharmaceutical preparation(including biochemicals)
Target Country / Area All Countries / Areas

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Detail Description

GLP certified testing of xenobiotics and chemicals

Our company is a contract research organization providing GLP-certified in vitro services for pharmaceutical and biotech companies.

We offer:
- Cytochrome P450 induction studies
- Cytochrome P450 inhibition studies
- Transporter Studies
- Toxicology Studies
- Analysis of hepatocellular function
- Uptake-Transporter Activities in HEK 293 cells
- Phototoxicity Testing

We are a provider of fresh and cryo-preserved primary human and animal cells

Major products are:
- Human Hepatocytes
- Cynomolgus Hepatocytes
- Beagle Hepatocytes
- Rat Hepatocytes
- Human Fibroblasts
- HEPAC2: A standardized, validated, re-usable human hepatocyte culture system
- HHMM: Human Hepatocyte Maintenance Medium for long-term serum-free cultivation of differentiated human hepatocytes
- We are certified according to GLP

We have successfully tested active pharmaceutical ingredients as well as plant derived extracts (herbal medicine) for Biotech and Pharmaceutical companies.
Our human hepatocyte culture system HEPAC2 has been shown to predict toxicological actions of drugs in humans correctly and more accurate than animal experiments:
Cis-4-Hydroxy-L-Proline has been evaluated as an anticancer drug in clinical studies, animal studies and human hepatocyte cultures.
The data gained from animal experiments suggested a limited toxicity of the substance and did not correlate with the data obtained in the clinical study. However, the results derived fromour human liver cell culture system HEPAC2 clearly demonstrated and predicted the harmlessness of the drug in humans correctly.
The results have been published (Molecular Medicine Reports, 1: 459-464, 2008.

User Info
Proposals Registered by this Corporation and User    (2 total matches)

Cryopreserved human and animal hepatocytes, cell culture media

Offer to sell products / parts

Mecklenburg-Vorpommern, Germany

Nov 27, 2009 RegistrationFeb 18, 2015 Revision

Total Sum of CONTACT Received : 3

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